Brian McEleney has directed Tony Kushner’s “Angels in America Part 2: Perestroika” at Warwick’s Gamm Theatre with perfection in his grasp.

The casting, the costumes, the lighting, the movement of the many interlocking scenes all come together in a production worthy of the praise that has been given to their presentation of Part 1.

The play begins with a call for change. It is the 1980s in America and we have been hit with an AIDS epidemic. The politics of men like Roy Cohn has crept into the country, causing political unrest.

Arrive a few minutes early and read the one-page summary in the program of Part 1, preparing you for three hours of intense theatre, as we are reintroduced to the characters.

From the arrogant Roy (Tony Estrella) to the flamboyant nurse Belize (Rodney Witherspoon II), we watch this outstanding cast portray characters who are frail, unhappy, in love, sick and victims of this terrible disease. We watch them grow, change and interact.

Pay close attention to the intermingling of scenes as characters become involved with each other in a variety of ways.

The second half is a bit darker as “the world spins forward” and people try to keep up with it, trying to deal with life’s many disappointments and inner turmoil.

If you have seen Part 1, Part 2 is a must.

At Gamm through October 12. Visit gammtheatre.org for tickets.